GENERAL CATALOGUE
Enpatoran
HY-134581 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-134581
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medchemexpress.com/enpatoran.htmlCatalog No: HY-134581
CAS No: 2101938-42-3
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Enpatoran M5049 is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran is inactive against TLR3, TLR4 and TLR9. Enpatoran can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran exhibits excellent pharmacokinetic properties in vivo. Enpatoran can be used for both innate and adaptive autoimmunity blocking research .