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Enpp-1-IN-19
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Enpp-1-IN-19

HY-155457 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-155457

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Manufacturer product page

medchemexpress.com/enpp-1-in-19.html
Catalog No: HY-155457
CAS No: 2738583-25-8
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Enpp-1-IN-19 compound 29f is an orally active ENPP1 inhibitor that inhibits cGAMP hydrolysis by ENPP1 IC50=68 nM . Enpp-1-IN-19 increases anti-PD-L1 responses and inhibits tumor growth in CT26 syngeneic models. Enpp-1-IN-19 also enhances STING-mediated type I interferon responses, induces immune memory, and prevents tumor recurrence.

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