GENERAL CATALOGUE
Entrectinib (Standard)
HY-12678R · 5 mg
MedChemExpress · Cat: HY-12678R
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medchemexpress.com/entrectinib-standard.html
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Catalog No: HY-12678R
CAS No: 1108743-60-7
Category: Autophagy
Pack Size: 5 mg
Brand: MedChemExpress
Description
Entrectinib Standard is the analytical standard of Entrectinib. This product is intended for research and analytical applications. Entrectinib NMS-E628 is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice.
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