GENERAL CATALOGUE
EP39
HY-150536 · 50 mg
MedChemExpress · Cat: HY-150536
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Catalog No: HY-150536
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
EP39 is a potent HIV-1 maturation inhibitor. EP39 interacts with the SP1 domain of Gag. EP39 decreases the dynamics of CA-SP1 junction, by binding to the QVT motif of the SP1 domain, and perturbs the natural coil-helix equilibrium on both sides of the SP1 domain by stabilizing the transient alpha helical structure. EP39 acts by arresting maturation of HIV-1 thereby blocking its infectivity.
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