GENERAL CATALOGUE
Epoxomicin
HY-13821 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13821
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Catalog No: HY-13821
CAS No: 134381-21-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Epoxomicin BU-4061T is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity.
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