BRAND STORE
EPPTB, TAAR1 antagonist
ab254331 · 10 mg
AB
Verified Partner
Sign in to see pricing and request a quote.
Brand Store Product
No external links. Get your quote directly here.
Sponsored
Catalog No: ab254331
Category: Biochemicals
Pack Size: 10 mg
Brand: abcam
Description
MW 378.4 Da, Purity >99 %. Novel, selective, highly potent trace amine associated receptor 1 TAAR1 antagonist. Higher potency in mouse than rat and human IC50 values are 28nM, 4539nM and 7487nM, respectively . Increases firing frequency of dopamine DA neurons in ventral tegmental area by blocking inward potassium current mediated by TAAR1, increasing DA activity on D2 receptor. Displays inverse agonism in vitro by reducing cAMP levels IC50 =19nM .
More from abcam
NYC-488, Calpain Inhibitor, calpain inhibitor
ab143563
Biochemicals
4-Hydrazino-7-nitrobenzofurazane hydrazine adduct
ab275359
Biochemicals
ABD-F, Fluorogenic reagent for thiol labeling
ab145273
Biochemicals
CNQX disodium salt (mM/ml), AMPA / kainate antagonist (water soluble)
ab144488
Biochemicals
Temocapril hydrochloride, ACE inhibitor
ab142951
Biochemicals
Fluvoxamine maleate, Serotonin reuptake inhibitor (SSRI)
ab141082
Biochemicals
Anisomycin, Protein synthesis inhibitor
ab120495
Biochemicals
PugNAc, hexosaminidase A and B inhibitor
ab144670
Biochemicals