GENERAL CATALOGUE
EpskA21
HY-161858 · 50 mg
MedChemExpress · Cat: HY-161858
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Manufacturer product page
medchemexpress.com/epska21.htmlCatalog No: HY-161858
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
EpskA21 is an inhibitor for PI3K/AKT signaling pathway, and inhibits the proliferation of cancer cells MCF-7, A549, MIA-PaCa-2, Panc-1 and HepG2, with IC50 of 1.3-7.24 ?M. EpskA21 inhibits the cell migration, arrests the cell cycle at G2/M MCF-7 and S MIA-PaCa-2 phase, and induces apoptosis in MCF-7 and MIA-PaCa-2. EpskA21 causes the mitochondrial dysfunction.
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