

HY-108531A · 1 mg
MedChemExpress · Cat: HY-108531A
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medchemexpress.com/er-50891-quarterhydrate.htmlDescription
ER 50891 quarterhydrate is a RAR? antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid ATRA on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin OCN expression and extracellular matrix mineralization, and suppresses alkaline phosphatase ALP activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis.







