ERK1 Mouse Monoclonal Antibody

Description

EnkiLife offers the ERK1 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for IHC application. Alternative Names of Immunogen: MAPK3. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:50-1:100 Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. Research Area: Apoptosis,TGF-beta signaling pathway,PI3K-Akt signaling pathway,mTOR signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway