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EZH2/HSP90-IN-29
GENERAL CATALOGUE

EZH2/HSP90-IN-29

HY-163288 · 50 mg

MedChemExpress · Cat: HY-163288

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Catalog No: HY-163288
CAS No: 3033571-35-3
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

EZH2/HSP90-IN-29 is a dual inhibitor for EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively. EZH2/HSP90-IN-29 increases apoptosis/necrosis-related gene expression, induces cell cycle arrest at M phase and inhibits reactive oxygen species ROS catabolism pathway. EZH2/HSP90-IN-29 is able to cross the blood-brain-barrier BBB .

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