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EZH2-IN-1
GENERAL CATALOGUE

EZH2-IN-1

HY-122595 · 50 mg

MedChemExpress · Cat: HY-122595

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Manufacturer product page

medchemexpress.com/ezh2-in-1.html
Catalog No: HY-122595
CAS No: 1377997-28-8
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

EZH2-IN-1 compound 3 is a selective and SAM-competitive EZH2 and EZH1 inhibitor with an IC50s of 32 nM, 197 nM and 213 nM for EZH2wt, EZH2 Y641N mutant and EZH1, respectively. EZH2-IN-1 reduces bulk H3K27me3 and H3K27me2 levels. EZH2-IN-1 has the potential for diffuse large B cell lymphoma research.

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