

HY-122595 · 50 mg
MedChemExpress · Cat: HY-122595
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medchemexpress.com/ezh2-in-1.htmlDescription
EZH2-IN-1 compound 3 is a selective and SAM-competitive EZH2 and EZH1 inhibitor with an IC50s of 32 nM, 197 nM and 213 nM for EZH2wt, EZH2 Y641N mutant and EZH1, respectively. EZH2-IN-1 reduces bulk H3K27me3 and H3K27me2 levels. EZH2-IN-1 has the potential for diffuse large B cell lymphoma research.

