GENERAL CATALOGUE
EZH2-IN-14
HY-148458 · 5 mg
MedChemExpress · Cat: HY-148458
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medchemexpress.com/ezh2-in-14.htmlCatalog No: HY-148458
CAS No: 1979157-17-9
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress
Description
EZH2-IN-14 is a selective EZH2 Histone Methyltransferase inhibitor with an IC50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 that is, reducing H3K27me3 . EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1.
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