GENERAL CATALOGUE
F-14512
HY-106031 · 5 mg
MedChemExpress · Cat: HY-106031
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medchemexpress.com/f-14512.htmlCatalog No: HY-106031
CAS No: 866874-63-7
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
F-14512 is an anticancer agent that utilizes the polyamine transport system PTS to selectively deliver polyamine-containing drugs to cancer cells. F-14512 enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 can be used to study breast cancer.
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