

HY-163436 · 1 mg
MedChemExpress · Cat: HY-163436
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Manufacturer product page
medchemexpress.com/f44-a13.html
Description
F44-A13 is an orally active and highly selective farnesoid X receptor FXR antagonist with an IC50 value of 1.1 ?M. F44-A13 can optimize cholesterol metabolism and reduce its activity by inducing CYP7A1 expression. F44-A13 reduces levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol LDL-C in mouse models. F44-A13 can be used in the study of metabolic diseases associated with lipid disorders.





