GENERAL CATALOGUE
F5446
HY-150190 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-150190
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Catalog No: HY-150190
CAS No: 2304465-89-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
F5446 Compound 1 is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo.
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