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F594-1001 hydrochloride
GENERAL CATALOGUE

F594-1001 hydrochloride

HY-160943A · 50 mg

MedChemExpress · Cat: HY-160943A

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Catalog No: HY-160943A
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

F594-1001 compound 6 hydrochloride is a potent and highly selective SARS-CoV-2 Mac1-ADP-ribose inhibitor with IC50s of 8.5 ?M, 68 ?M and 45 ?M for SARS-CoV-2 in AS, FP, and FRET assays, respectively. F594-1001 hydrochloride directly binds to SARS-CoV-2 Mac1 and exhibits a dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity.

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