FADD Rabbit Polyclonal Antibody

Description

EnkiLife offers the FADD Rabbit Polyclonal Antibody. This antibody reacts with Mouse species and is suitable for WB,IHC,FC application. Alternative Names of Immunogen: FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100 Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Research Area: Cell Biology