GENERAL CATALOGUE
Farudodstat
HY-129239 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-129239
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Catalog No: HY-129239
CAS No: 1035688-66-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Farudodstat ASLAN003 is an orally active and potent Dihydroorotate Dehydrogenase DHODH inhibitor with an IC50 of 35 nM for human DHODH enzyme. Farudodstat inhibits protein synthesis via activation of AP-1 transcription factors. Farudodstat induces apoptosis and substantially prolongs survival in acute myeloid leukemia AML xenograft mice.
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