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Fasudil dihydrochloride
GENERAL CATALOGUE

Fasudil dihydrochloride

HY-10341C · 25 mg

MedChemExpress · Cat: HY-10341C

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Catalog No: HY-10341C
CAS No: 203911-27-7
Category: Anti-infection
Pack Size: 25 mg
Brand: MedChemExpress

Description

Fasudil HA-1077; AT877 dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 ?M for ROCK1, IC50s of 0.158 ?M and 4.58 ?M, 12.30 ?M, 1.650 ?M for ROCK2 and PKA, PKC, PKG, respectively. Fasudil dihydrochloride is also a potent Ca2+ channel antagonist and vasodilator.

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