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Fasudil hydrochloride semihydrate
GENERAL CATALOGUE

Fasudil hydrochloride semihydrate

HY-10341B · 50 mg

MedChemExpress · Cat: HY-10341B

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Catalog No: HY-10341B
CAS No: 186694-02-0
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

Fasudil HA-1077; AT877 hydrochloride semihydrate is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 ?M for ROCK1, IC50s of 0.158 ?M and 4.58 ?M, 12.30 ?M, 1.650 ?M for ROCK2 and PKA, PKC, PKG, respectively. Fasudil hydrochloride semihydrate is also a potent Ca2+ channel antagonist and vasodilator.

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