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Fasudil mesylate
GENERAL CATALOGUE

Fasudil mesylate

HY-10341D · 50 mg

MedChemExpress · Cat: HY-10341D

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Catalog No: HY-10341D
CAS No: 1001206-62-7
Category: Autophagy
Pack Size: 50 mg
Brand: MedChemExpress

Description

Fasudil HA-1077; AT877 mesylate is a nonspecific and orally active RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 ?M for ROCK1, IC50s of 0.158 ?M and 4.58 ?M, 12.30 ?M, 1.650 ?M for ROCK2 and PKA, PKC, PKG, respectively. Fasudil mesylate is also a potent Ca2+ channel antagonist and vasodilator.

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