

HY-14452A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-14452A
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medchemexpress.com/fatostatin-hydrobromide.htmlDescription
Fatostatin hydrobromide 125B11 hydrobromide , a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP SREBP cleavage-activating protein , and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice.







