GENERAL CATALOGUE
Fazirsiran
HY-132604 · 1 mg
MedChemExpress · Cat: HY-132604
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medchemexpress.com/fazirsiran.html
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Catalog No: HY-132604
CAS No: 2175009-08-0
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress
Description
Fazirsiran ARO-AAT is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger chol-RNAi to selectively degrade Alpha1-antitrypsin AAT mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine NAG formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes. Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency AATD liver disease.
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