GENERAL CATALOGUE
FC-116
HY-155068 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-155068
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Catalog No: HY-155068
CAS No: 2417298-29-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
FC-11 is a tubulin inhibitor. FC-116 inhibits the proliferation of colorectal cancer CRC cells, with IC50 values of 4.52 nM for HCT116 cells and 18.69 nM for CT26 cells. FC-11 can induce ER stress to generate excess ROS, leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer CRC cells by targeting microtubules. FC-116 exerts potent anti-tumor effects in vivo. FC-11 can be used for the study of colorectal cancer.
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