

HY-111662 · 50 mg
MedChemExpress · Cat: HY-111662
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medchemexpress.com/fc-11a-2.htmlDescription
Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium DSS; HY-116282C -induced murine experimental colitis.







