GENERAL CATALOGUE
FC-14367
HY-171859 · 50 mg
MedChemExpress · Cat: HY-171859
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medchemexpress.com/fc-14367.html
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Catalog No: HY-171859
CAS No: 3066893-65-7
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
FC-14367 is a PROTAC degrader targeting HIV-1 Nef protein. FC-14367 forms a ternary complex by binding Nef and Cereblon E3 ubiquitin ligase, inducing Nef ubiquitination and proteasomal degradation, restoring cell-surface CD4 and MHC-I expression and inhibiting HIV-1 replication. FC-14367 can be used in research on HIV infection and AIDS. Black: Glycolic acid HY-W015967 ; Blue: 2- 2,6-Dioxopiperidin-3-yl phthalimidine HY-138793
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