GENERAL CATALOGUE
FCN-338
HY-175342 · 50 mg
MedChemExpress · Cat: HY-175342
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medchemexpress.com/fcn-338.html
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Catalog No: HY-175342
CAS No: 2248046-39-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
FCN-338 LOXO-338 is an orally active and selective Bcl-2 inhibitor with an IC50 of 4.5 nM for Bcl-2/BAK interaction. FCN-338 potently inhibits tumor growth in follicular lymphoma FL , acute myeloid leukemia AML , and acute lymphoblastic leukemia ALL xenograft mice model without significant weight loss. FCN-338 has a broad-spectrum anti-cancer activity, such as FL, CLL/SLL, AML, and ALL.
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