

HY-128570 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128570
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medchemexpress.com/fd-in-1.htmlDescription
FD-IN-1 Compound 12 is an orally bioavailable and selective factor D FD inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa FXIa and Tryptase ?2 with IC50s of 7.7 and 6.5 AAasAasAAmuM, respectively.







