

HY-10409 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10409
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Manufacturer product page
medchemexpress.com/TG-101348.html
Description
Fedratinib TG-101348 is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.







