GENERAL CATALOGUE
Fedratinib hydrochloride hydrate
HY-10409A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10409A
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Manufacturer product page
medchemexpress.com/fedratinib-hydrochloride-hydrate.htmlCatalog No: HY-10409A
CAS No: 1374744-69-0
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Fedratinib hydrochloride hydrate TG-101348 hydrochloride hydrate is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.
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