GENERAL CATALOGUE
FEN1-IN-7
HY-153792 · 1 mg
MedChemExpress · Cat: HY-153792
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medchemexpress.com/fen1-in-7.htmlCatalog No: HY-153792
CAS No: 824983-90-6
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
FEN1-IN-7 compound 16 is a selective inhibitor of Flap endonuclease-1 FEN1, IC50=18 nM , involving in mammalian cells to repair DNA damage. FEN1-IN-7 also targets to related endonuclease, xeroderma pigmentosum G XPG with an IC50 value of 3.04 ?M. FEN1-IN-7 increases the cellular sensitivity of cancer cells to potent DNA alkylating agents or methylating agents.
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