GENERAL CATALOGUE
Fenobam
HY-101478 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-101478
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medchemexpress.com/fenobam.html
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Catalog No: HY-101478
CAS No: 57653-26-6
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Fenobam is a selective and orally active mGluR5 antagonist IC50=84 nM that can penetrate the blood-brain barrier. Fenobam shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam has anxiolytic activity, inhibits self-administration behavior in mice, and induces apoptosis in cancer cells. Fenobam can be used for research on neurological diseases, cancer and drug addiction.
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