GENERAL CATALOGUE
Fenobam hydrate
HY-101478A · 50 mg
MedChemExpress · Cat: HY-101478A
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Catalog No: HY-101478A
CAS No: 63540-28-3
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Fenobam hydrate is a selective and orally active mGluR5 antagonist IC50=84 nM that can penetrate the blood-brain barrier. Fenobam hydrate shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam hydrate has anxiolytic activity, inhibits self-administration behavior in rat, and induces apoptosis in cancer cells. Fenobam hydrate can be used for research on neurological diseases, cancer and drug addiction.
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