Ferroptosis-IN-17

Description

Ferroptosis-IN-17 Compound 18 is a ferroptosis Ferroptosis inhibitor with an EC50 value of 0.57 ?M. Ferroptosis-IN-17 reduces intracellular ferrous ion accumulation, lipid peroxidation, and effectively restores the levels of glutathione GSH and glutathione peroxidase 4 GPX4 . Ferroptosis-IN-17 shows good solubility and significant metabolic stability in rat plasma. Ferroptosis-IN-17 is promising for research in tumor suppression, neurodegenerative diseases, and cardiovascular diseases.