GENERAL CATALOGUE
FGA139
HY-172977 · 50 mg
MedChemExpress · Cat: HY-172977
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Manufacturer product page
medchemexpress.com/fga139.htmlCatalog No: HY-172977
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
FGA139 is a cysteine proteases inhibitor with IC50 values of 4.98/3.14 ?M for cathepsin B/L. FGA139 reduces LPS-induced NO production in RAW264.7 cells and tumor necrosis factor TNF? levels in microglia, and has anti-oxidative stress and anti-inflammatory activities. FGA139 promotes the secretion of neuroprotective metabolites purine and linoleic acid by LPS-stimulated microglia. FGA139 can be used in neuroinflammatory diseases research.
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