

HY-148597 · 50 mg
MedChemExpress · Cat: HY-148597
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medchemexpress.com/fgfr-in-10.htmlDescription
FGFR-IN-10 is an orally active inhibitor of FGFR and Cytochrome P450 CYPs . FGFR-IN-10 inhibits wide type and V564F mutant FGFR2 with IC50s of 104.1 nM and 43.6 nM, respectively. FGFR-IN-10 also inhibits CYPs with IC50s of 3.33 ?M CYP2C9 , 18.75 ?M CYP2C19 , 4.34 ?M CYP2CD6 , and 0.69 ?M CYP3A4 , respectively.







