GENERAL CATALOGUE
FGFR-IN-8
HY-150652 · 50 mg
MedChemExpress · Cat: HY-150652
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medchemexpress.com/fgfr-in-8.htmlCatalog No: HY-150652
CAS No: 2640217-64-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
FGFR-IN-8 Compound 17a is a highly potent and orally active panFGFR inhibitor against wild-type and mutant FGFRs. FGFR-IN-8 shows inhibition with IC50 values of <0.5, 189.1, <0.5, 22.6, <0.5 and 7.30 nM against FGFR1, V564F-FGFR2, N549H-FGFR2, V555M-FGFR3, FGFR3 and FGFR4, respectively. GFR-IN-8 induces cancer cell apoptosis and shows anticancer activities.
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