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FHND5032
GENERAL CATALOGUE

FHND5032

HY-174976 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-174976

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Manufacturer product page

medchemexpress.com/fhnd5032.html
Catalog No: HY-174976
CAS No: 3076057-63-8
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

FHND5032 is an orally active miR-124 inducer. FHND5032 significantly upregulates miR-124 expression in macrophages. FHND5032 disrupts inflammatory signaling, promotes macrophage reprogramming, and restores the epithelial barrier function by inhibiting the PIK3R2/PI3K/Akt axis. FHND5032 alleviates colitis and reduces inflammatory burden in ulcerative colitis mice. FHND5032 can be used for the study of ulcerative colitis.

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