GENERAL CATALOGUE
Filgotinib
HY-18300 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-18300
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medchemexpress.com/GLPG0634.html
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Catalog No: HY-18300
CAS No: 1206161-97-8
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Filgotinib GLPG0634 is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1, JAK2, JAK3 and TYK2 with IC50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
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