GENERAL CATALOGUE
FKK6
HY-168328 · 5 mg
MedChemExpress · Cat: HY-168328
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Catalog No: HY-168328
CAS No: 2238839-34-2
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
FKK6 is a selective agonist for pregnane X receptor PXR with an EC50 of 1.2 AAasAasAAmuM. FKK6 exhibits good affinity with plasma proteins, and good metabolic metabolism in human microsomes. FKK6 inhibits PXR-related NF-?B signaling pathway, inhibits the expression of inflammatory factors, and exhibits anti-inflammatory activity against DSS HY-116282 -induced colitis in mouse model.
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