

T6249 · 1 x 106 cells / 1.0 mL
abm good · Cat: T6249
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abmgood.com/flag-lbmbt1-stable-expressing-hek293-cell-line.h...
Description
Malignant-brain-tumor MBT protein L3MBTL1 is in a complex comprised of core histones, histone H1b, HP1g, and Rb. In humans, L3MBTL1 is a known transcriptional repressor, which requires its three MBT domains for silencing. This cell line is useful to study the transcriptional repression linked to the formation and maintenance of facultative heterochromatin and the mechanism behind Histone-Methylation Dependent Chromatin Lock.