Florzolotau

Description

Florzolotau APN1607 is a positron emission tomography PET ligand that can be used to detect Alzheimers disease AD and other tau proteinopathies. Its binding sites are located in the ?-helix of the paired helical filaments PHFs and straight filaments SFs of the tau protein, as well as in the C-shaped cavity of the SFs. In addition, APN-1607 can bind to the intraneuronal inclusions in Alzheimers disease AD , primary age-related tauopathy PART , and posterior cortical atrophy PCA . Florzolotau is expected to be used in PET imaging research of neurological diseases, especially tau proteinopathies.