GENERAL CATALOGUE
FLT3-IN-14
HY-144777 · 50 mg
MedChemExpress · Cat: HY-144777
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Manufacturer product page
medchemexpress.com/flt3-in-14.htmlCatalog No: HY-144777
CAS No: 2620551-45-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
FLT3-IN-14 is a potent FLT3 inhibitor with IC50s of 5.6 nM and 1.4 nM for FLT3-WT and FLT3-ITD. FLT3-IN-14 reduces the phosphorylation of FLT3 Y591 , induces cell cycle arrest at G1 phase and apoptosis. FLT3-IN-14 significantly reduces the tumor growth in an MV4-11 xenograft mouse model.
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