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FLT3/TrKA-IN-1
GENERAL CATALOGUE

FLT3/TrKA-IN-1

HY-146749 · 50 mg

MedChemExpress · Cat: HY-146749

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Catalog No: HY-146749
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

FLT3/TrKA-IN-1 is a potent FLT3/TrKA dual kinase inhibitor with the IC50s of 43.8 nM, 97.2 nM, 92.5 nM and 23.6 nM for FLT3, FLT3-ITD, FLT3-TKD and TrKA, respectively. FLT3/TrKA-IN-1 induces cell cycle arrest at the G0/G1 phase as well as apoptosis and shows antiproliferative activity in vitro. FLT3/TrKA-IN-1 has the potential for the research of Acute myeloid leukemia AML .

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