GENERAL CATALOGUE
Fludarabine triphosphate
HY-136650 · 50 mg
MedChemExpress · Cat: HY-136650
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medchemexpress.com/fludarabine-triphosphate.htmlCatalog No: HY-136650
CAS No: 74832-57-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Fludarabine triphosphate F-ara-ATP , the active metabolite of Fludarabine HY-B0069 , is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 ?M and a Ki of 6.1 ?M. Fludarabine triphosphate inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
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