Fmoc-L-Lys(Pentynoyl-DIM)-OH

Description

Fmoc-L-Lys Pentynoyl-DIM -OH is a click chemistry reagent containing an azide. Fmoc-L-Lys Pentynoyl-DIM -OH can be used as a SPPS building block for the AAasAasAahelping handAAasAasAa strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition SPAAC with molecules containing DBCO or BCN groups.