GENERAL CATALOGUE
Fosmidomycin
HY-134914 · 50 mg
MedChemExpress · Cat: HY-134914
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Catalog No: HY-134914
CAS No: 66508-53-0
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase DOXP reductoisomerase . Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin HY-B1455 , and ameliorates malaria in mouse model.
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