
ab235552 · 5 mg
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Description
MW 327.8 Da, Purity >98 %. High-affinity, blood-brain-barrier permeable, non-toxic, tertiary amide RAGE Receptor for Advanced Glycation End products receptor antagonist Ki = 25 nM . Blocks Abeta binding to the V domain of RAGE. Inhibits Abeta40- and Abeta42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo.






