GENERAL CATALOGUE
Framycetin
HY-17624 · 25 mg (16.27 mM * 2.5 mL in 0.9% NaCl)
MedChemExpress · Cat: HY-17624
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Catalog No: HY-17624
CAS No: 119-04-0
Category: Anti-infection
Pack Size: 25 mg (16.27 mM * 2.5 mL in 0.9% NaCl)
Brand: MedChemExpress
Description
Framycetin Neomycin B , an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 ?M. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 ?M. Framycetin, a 5?-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.
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