Frovatriptan-d3 succinate

Description

Frovatriptan-d3 succinate is deuterium labeled Frovatriptan succinate . Frovatriptan succinate R -Frovatriptan succinate is a potent, high affinity, selective and orally active 5-HT1B pK50 of 8.2 and 5-HT1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and ?1-adrenoceptor. Frovatriptan succinate has the potential for migraine research.